kosta jeezy
New Member
Femara: Letrozole
I've had a lot of people over the years asked me to common questions:
1) I don't think my regular ai dosing is in point... and my estrogen appears to be high how can I bring that down?
&
2) what is letrozole? And how is it best used???
I can sum up both of those questions with one answer...
Letrozole, also known as Femara, is a nonsteroidal competitive inhibitor of the aromatase enzyme system; it inhibits the conversion of androgens to estrogens. There is basically two times when letrozole is best to be used... to bring down high levels of estrogen and gyno side effects (if you have had them then you know how annoying they can be). But letrozole is also great for the finisher of a cycle to dry out. Many body builders use it at the end of their cycles for just that reason, but also many end up using multiple compounds (test, primo, whinny, anavar, major aromatizing compounds, etc) and need something to completely control the levels.
So why don't people use letrozole on a regular basis over other lesser AIs? This is because letrozole is a much more powerful AI, and in many cases to powerful for usage. Letrozole basically kills your estrogen level completely, and properly balanced hormone levels are essential for the body to work correctly.
Helpful Additional Technical Data:
Letrozole is rapidly and completely absorbed from the gastrointestinal tract and absorption is not affected by food. It is metabolized slowly to an inactive metabolite whose glucuronide conjugate is excreted renally, representing the major clearance pathway. About 90% of radiolabeled letrozole is recovered in urine. Letrozole's terminal elimination half-life is about 2 days and steady-state plasma concentration after daily 2.5 mg dosing is reached in 2-6 weeks
I've had a lot of people over the years asked me to common questions:
1) I don't think my regular ai dosing is in point... and my estrogen appears to be high how can I bring that down?
&
2) what is letrozole? And how is it best used???
I can sum up both of those questions with one answer...
Letrozole, also known as Femara, is a nonsteroidal competitive inhibitor of the aromatase enzyme system; it inhibits the conversion of androgens to estrogens. There is basically two times when letrozole is best to be used... to bring down high levels of estrogen and gyno side effects (if you have had them then you know how annoying they can be). But letrozole is also great for the finisher of a cycle to dry out. Many body builders use it at the end of their cycles for just that reason, but also many end up using multiple compounds (test, primo, whinny, anavar, major aromatizing compounds, etc) and need something to completely control the levels.
So why don't people use letrozole on a regular basis over other lesser AIs? This is because letrozole is a much more powerful AI, and in many cases to powerful for usage. Letrozole basically kills your estrogen level completely, and properly balanced hormone levels are essential for the body to work correctly.
Helpful Additional Technical Data:
Letrozole is rapidly and completely absorbed from the gastrointestinal tract and absorption is not affected by food. It is metabolized slowly to an inactive metabolite whose glucuronide conjugate is excreted renally, representing the major clearance pathway. About 90% of radiolabeled letrozole is recovered in urine. Letrozole's terminal elimination half-life is about 2 days and steady-state plasma concentration after daily 2.5 mg dosing is reached in 2-6 weeks
