Crashed Libido on Test/Primo/Anavar

[HoldenHoffman]

Hi all,
Currently I am on week 10 of a planned 20 week cycle. This is my first real planned and thought out cycle of this duration. Plan was to start at 200 test/200 primo with 6.25 mg of Anavar PWO everyday (mostly for collagen support as about 6 months out from an elbow surgery). Daily injections of Test/Primo in the glute or delts with slin pin. Then titrate up every 4-6 weeks after getting bloodwork. Was feeling my pretty good with good progress after first 6 weeks. Overall so far I have dropped a good amount of body fat while gaining strength in a very slow cut/recomp (1500ish weekly calorie deficit)

Got the following bloods back after week 6
CBC with Differential/Platelet: all normal within Range
Lipids: LDL 75, HDL 25
Testosterone: 995
Ultrasensitive E2: 10.7
Blood pressure checked daily always under 120/70

Following these labs I added in Citrus Bergamot and Niacin to my normal supplement stack to try to improve lipids.
I also upped the dose of testosterone dose to 250mg a week to attempt to raise E2 levels more towards the center of the reference range and progress the cycle.

Over the last few weeks I have noticed my libido is progressively becoming non existent and have no interest in sexual activity. Although normal function is still intact.

Other supplements of note
5mg Cialis before bed
20mg Telemartisan PWO
500mcg/500mcg/2.5mg BPC/TB500/GHK AM/PM
500mg Injectable L Carnatine PWO

Was curious for any ideas or solutions what may be causing the crashed libido. Also some ideas for other blood tests to order when I go get labs done in the next week or so that may help me find the root cause of this issue. My original plan was to progress to 300 test 250 primo for the end of my cycle if the labs come back alright.

 

[xrayphoton13]

Yeah e2 is crashed. Get it 3 times higher to 30 and see how you feel. 50mg test isn't gonna do much to raise your e2. Drop the primo to 100mg, leave the test at 250mg and that might work. Running primo at the same dose as test is a recipe for crashed e2. Usually you would do half primo and see how your ultra sensitive e2 responds after 6 weeks. HCG 250iu 3x per week could help raise e2 as well. Dbol will give methyl e2 which feels the same but can't be measured on lab work. Probably not a good choice if cutting due to water. Dhea can be used temporarily to raise e2 while you get your AAS doses worked out. Low Estradiol? Here's How DHEA Can Fix Your "Crashed" E2

Oh and check your shbg next time if you want. Sometimes people get in the single digits and complain of no sex drive either. But usually it's from crashed e2

 

[MadaFacor]

@xrayphoton13 has the answer. E2 is way to low. Reduce or drop the Pimo. Or up the Test. Or add in a compound that will spike E2.

 

[HoldenHoffman]

Yeah e2 is crashed. Get it 3 times higher to 30 and see how you feel. 50mg test isn't gonna do much to raise your e2. Drop the primo to 100mg, leave the test at 250mg and that might work. Running primo at the same dose as test is a recipe for crashed e2. Usually you would do half primo and see how your ultra sensitive e2 responds after 6 weeks. HCG 250iu 3x per week could help raise e2 as well. Dbol will give methyl e2 which feels the same but can't be measured on lab work. Probably not a good choice if cutting due to water. Dhea can be used temporarily to raise e2 while you get your AAS doses worked out. Low Estradiol? Here's How DHEA Can Fix Your "Crashed" E2

Oh and check your shbg next time if you want. Sometimes people get in the single digits and complain of no sex drive either. But usually it's from crashed e2

@xrayphoton13 has the answer. E2 is way to low. Reduce or drop the Pimo. Or up the Test. Or add in a compound that will spike E2.

Appreciate the advice gentlemen. I was hoping the increase from 200 to 250 4 weeks ago would at least get me going in the right direction for the next blood test and then I could continue to adjust. However based off how I am feeling would it be reasonable to up my testosterone dose to 300mg and hold off on the expensive sensitive E2 test for a few more weeks? I did have a bad gyno flare last year from 250 test and 250 hcg 3x a week but I was at a much higher body fat then so not sure if I’m still as sensitive to gyno. Plenty of Aromasin and Raloxiphene on hand this time just in case. Still I’d like to avoid throwing in another compound like HCG or DHEA at this time just for simplicity.

 

[MadaFacor]

Appreciate the advice gentlemen. I was hoping the increase from 200 to 250 4 weeks ago would at least get me going in the right direction for the next blood test and then I could continue to adjust. However based off how I am feeling would it be reasonable to up my testosterone dose to 300mg and hold off on the expensive sensitive E2 test for a few more weeks? I did have a bad gyno flare last year from 250 test and 250 hcg 3x a week but I was at a much higher body fat then so not sure if I’m still as sensitive to gyno. Plenty of Aromasin and Raloxiphene on hand this time just in case. Still I’d like to avoid throwing in another compound like HCG or DHEA at this time just for simplicity.

Gyno is not something I know much about. Appears I seem to not be susceptible to it. Have had E2 test around 120 and felt like a goddamn king. HCG is infamous for spiking E2 so I think you have your culprit. What I have read, if you are susceptible to gyno,it will not likely will not go away unless you get the glands removed. If I were you, I would drop down the Primo immediately, but keep it in. Run that for 3 to 4 weeks and see if you start feeling better. If so then get your testing done. See where you leveled out at and note that.

 

[HoldenHoffman]

Gyno is not something I know much about. Appears I seem to not be susceptible to it. Have had E2 test around 120 and felt like a goddamn king. HCG is infamous for spiking E2 so I think you have your culprit. What I have read, if you are susceptible to gyno,it will not likely will not go away unless you get the glands removed. If I were you, I would drop down the Primo immediately, but keep it in. Run that for 3 to 4 weeks and see if you start feeling better. If so then get your testing done. See where you leveled out at and note that.

Think I’m going to end up raising my test to 300 and leaving Primo at 200 for 3-4 weeks then pulling bloodwork. If that doesn’t work and I still feel like shit I’ll drop the Primo to 150. But I’m too stubborn right now to drop the Primo dose.

 

[BigDadd7]

Lower the primo and up the test

 

[xrayphoton13]

Appreciate the advice gentlemen. I was hoping the increase from 200 to 250 4 weeks ago would at least get me going in the right direction for the next blood test and then I could continue to adjust. However based off how I am feeling would it be reasonable to up my testosterone dose to 300mg and hold off on the expensive sensitive E2 test for a few more weeks? I did have a bad gyno flare last year from 250 test and 250 hcg 3x a week but I was at a much higher body fat then so not sure if I’m still as sensitive to gyno. Plenty of Aromasin and Raloxiphene on hand this time just in case. Still I’d like to avoid throwing in another compound like HCG or DHEA at this time just for simplicity.

You can push test to 300 but you'll still want to cut the primo to 100 at least until you get your labs on it. 300 test/200 primo could still result in low e2. Or if you just want to change one variable at a time: 400mg test/200mg primo

 

[ackmack78]

Id up the test to 300 and drop the primo to 150

 

[RockyP]

It’s been said already but lower primo
Increase test
Add 100 mg DHEA daily for a few weeks to get your E2 up in the short term.

 

[bigead]

I'm on 300 tc, 200 deca and 150 primo, dbol 25mg pre work out right now and no e2 issues feel great and boners for days. I basically use the primo for e2 control

 

[RockyP]

I'm on 300 tc, 200 deca and 150 primo, dbol 25mg pre work out right now and no e2 issues feel great and boners for days. I basically use the primo for e2 control

That's a nice stack right there - I'm finding a lot of folks like to run primo or mast (or EQ) with their nandrolone to keep that E2 on the low end - seems to help with sides since the nandrolone sensitizes the E2 receptor / exacerbates E2 sides. My "blast" in the winter months will be something like 400 test / 300 primo / 200 NPP. Just need to make sure you know what dose of primo / EQ does to your E2 for any given test dosage, and this changes over time if you lean out - i learned that the hard way. Kept my dosages the same and cut a lot of BF and when I checked my bloods the E2 was in the shitter.

 

[SauceBoss]

mast did this to me. Prolactin was high. P5P got me back in order in 10 days.

 

[Eddie.]

Think I’m going to end up raising my test to 300 and leaving Primo at 200 for 3-4 weeks then pulling bloodwork. If that doesn’t work and I still feel like shit I’ll drop the Primo to 150. But I’m too stubborn right now to drop the Primo dose.

If you don't want to reduce primo then bump the test to 400. At 300 you still gonna have low e2, i very much doubt going from 200 to 300 test could triple your e2.

 

[HoldenHoffman]

Realized that I completely neglected to consider the RU58841 spray I’ve been using. Have seen some claims that this can sometimes go systemic and cause issues due to DHT blockage. Any chance this could be contributing to continued issues after raising test and lowering primo?

 

[amazonas]

Even when my e2 was in perfect range, primo always fucked up my libido completely. Just throwing it out there. There are many people reporting reduced libido on it. I know because i've ran it with every single combination out there.

 

[Eddie.]

This is true ^^ there are many guys complaining for libido on primo, i used it 2 times and both times first 3-4 weeks my sex drive was down but after that it came back stronger than before. To me primo gives a better libido than mast.

 

[Pombero]

Anavar tanks my SHBG to single digits quickly, and once that happens all libido is gone. In the teens it is fine, single digits nothing.

 

[HoldenHoffman]

Labs came back after 3 weeks of 300/200 Test/Primo
CBC with Differential/Platelet: all normal within Range (improved even from last bloodwork)
Lipids: LDL 98, HDL 25
Testosterone: >1500
Ultrasensitive E2: 17.2
CMP: AST ALT elevated (57 and 65) all else normal

Libido still crashed should’ve listened to y’all
Thinking of dropping Anavar completely and Primo down to 150 for my last 4 weeks.

 

[ackmack78]

Labs came back after 3 weeks of 300/200 Test/Primo
CBC with Differential/Platelet: all normal within Range (improved even from last bloodwork)
Lipids: LDL 98, HDL 25
Testosterone: >1500
Ultrasensitive E2: 17.2
CMP: AST ALT elevated (57 and 65) all else normal

Libido still crashed should’ve listened to y’all
Thinking of dropping Anavar completely and Primo down to 150 for my last 4 weeks.

Test 350 primo 150, don't just lower the primo. Personally I would jump to 350 test but right now throw an extra 100mg in one shot on top of that if I wanted it to come up quick. All depends on how you feel