BigOldBastard
New Member
Does anyone have a good method for mixing filler with active ingredient when the active ingredient is significantly smaller in weight than the filler? Trying to get as close to accurate dosing as possible per capsule.
MESO-Rx
Anabolic Steroids
Blending raws with filler
- Thread starter BigOldBastard
- Start date
narta
Member
volumetric dillution (google it)
Drugsarefun
New Member
Trituration Method (Capsules)
Guide from The Pharmaceutics and Compounding Laboratory at UNC
Mixing The Powder
Things you'll need: Milligram scale, small scoop, mortar & pestle, math.
Fill one capsule with your active ingredient. weigh on the milligram scale. record weight.
Fill one capsule with your filler. weigh on the milligram scale. record weight.
Find your ratio of active ingredient/filler (asin/creatine) using the formula -(Desired active dose x total filler)/total active-. This will give you how much space your active ingredient takes up out of a full capsule of your filler. I will use aromasin and creatine as an example. (THESE ARE EXAMPLE CAPACITIES, WEIGH YOUR OWN) One size 1 capsule holds 300mg asin, and 340mg creatine. To find out how much creatine to take out to account for 12.5mg of asin you follow the formula. (12.5 x 340)/300 = 14.166. 12.5mg of aromasin takes up the same amount of space as 14.166mg of creatine. You will be filling one capsule with 12.5mg asin, 325.8mg creatine. Multiply to meet your capsule requirements. So for 100 caps you would need 1.25g asin, 32.58g creatine.
Place your active ingredient in the mortar and pestle. 1.25g of aromasin. (This is where we use geometric dilution to achieve a thorough blend.)
Weigh out 1.25g of creatine, place in the mortar, and mix.
Weigh out 2.5g of creatine, place in mortar, and mix.
Weigh out 5g of creatine, place in mortar, and mix.
Repeat until desired quantity of powder is achieved.
Begin capping process with your newly mixed powder.
Can't remember the source but this is the method I use.
Guide from The Pharmaceutics and Compounding Laboratory at UNC
Mixing The Powder
Things you'll need: Milligram scale, small scoop, mortar & pestle, math.
Fill one capsule with your active ingredient. weigh on the milligram scale. record weight.
Fill one capsule with your filler. weigh on the milligram scale. record weight.
Find your ratio of active ingredient/filler (asin/creatine) using the formula -(Desired active dose x total filler)/total active-. This will give you how much space your active ingredient takes up out of a full capsule of your filler. I will use aromasin and creatine as an example. (THESE ARE EXAMPLE CAPACITIES, WEIGH YOUR OWN) One size 1 capsule holds 300mg asin, and 340mg creatine. To find out how much creatine to take out to account for 12.5mg of asin you follow the formula. (12.5 x 340)/300 = 14.166. 12.5mg of aromasin takes up the same amount of space as 14.166mg of creatine. You will be filling one capsule with 12.5mg asin, 325.8mg creatine. Multiply to meet your capsule requirements. So for 100 caps you would need 1.25g asin, 32.58g creatine.
Place your active ingredient in the mortar and pestle. 1.25g of aromasin. (This is where we use geometric dilution to achieve a thorough blend.)
Weigh out 1.25g of creatine, place in the mortar, and mix.
Weigh out 2.5g of creatine, place in mortar, and mix.
Weigh out 5g of creatine, place in mortar, and mix.
Repeat until desired quantity of powder is achieved.
Begin capping process with your newly mixed powder.
Can't remember the source but this is the method I use.
Might be a stupid question but, Instead of doubling the filler each time… would it be a safe assumption that using smaller amounts of filler each time, would be mixed even better?
